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Tenth International Symposium on
Mass Spectrometry in the Health & Life Sciences:
Molecular & Cellular Proteomics

Program

August: 21 | 22 | 23 | 24 | 25

Sunday, August 21

Symposium Registration
Nikko Ballroom Vestibule, Hotel Nikko, 222 Mason Street, San Francisco

3:00 - 5:30pm Registration

Monterey & Carmel Rooms

4:00pm Symposium Poster Set-up

Golden Gate Room, 25th floor

6:00pm Opening Reception

Monday, August 22

Nikko Ballroom Vestibule

7:30am Registration

Symposium
Nikko Ballroom

8:15am Introduction
A.L. Burlingame and John Stults

Chair: John Stults, Genentech, Inc., South San Francisco, California, USA

8:30am 1.1 Plenary Lecture
The Architecture and transport mechanism of the nuclear pore complex
Michael P. Rout, The Rockefeller University, New York, New York, USA

Chair: John Stults, Genentech, Inc., South San Francisco, California, USA

9:30 1.2 Development of mass spectrometer systems for resonance electron capture ionization and radio-frequency-free collision-induced and electron-capture dissociation
Douglas F. Barofsky, Oregon State University, Corvallis, Oregon, USA
10:10 Coffee break
10:30 1.3 Structural determination of biological macromolecules using ETD implemented on a hybrid ion mobility quadrupole time-of-flight mass spectrometer
Keith Compson, Waters Corporation, Manchester, UK
11:10 1.4 How high mass accuracy measurements will transform targeted proteomics
Joshua Coon, University of Wisconsin, Madison, Wisconsin, USA
11:50 1.5 Discovery and preliminary characterization of new lysine modifications
Yingming Zhao, University of Chicago, Illinois, USA
12:30pm Lunch

Chair: A.L. Burlingame, University of California, San Francisco, California, USA

2:00 1.6 Phosphatase interactomes — towards a quantitative view of interaction dynamics
Anne-Claude Gingras, Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario, Canada
2:40 The MCP Lectureship
Barbara Gordon, ASBMB, Bethesda, Maryland, USA
2:45 1.7 MCP Plenary Lecture
Technology and applications of deep proteome sequencing
Matthias Mann, Max Planck Institute of Biochemistry, Martinsried, Germany

Symposium Poster Session A
Monterey & Carmel Rooms

Co-Chairs: Shenheng Guan and David Maltby, University of California, San Francisco, California, USA

4:00 Poster Session A

Tuesday, August 23

Symposium
Nikko Ballroom

Chair: Barbara Panning, University of California, San Francisco, California, USA

8:30am 2.1 Plenary Lecture
The ATAC acetyltransferase complex coordinates the association and activity of MAP kinases on JNK target genes
Jerry Workman, Stowers Institute for Medical Research, Kansas City, Missouri, USA

Chair: Joshua Coon, University of Wisconsin, Madison, Wisconsin, USA

9:30 2.2 Long distance combinatorial histone posttranslational modification changes in DNA damage response and repair processes
Nicolas L. Young, Princeton University, New Jersey, USA
10:10 Coffee break
10:30 2.3 The good, the bad, and the ugly of using ChIP antibodies as tools to study histone modifications: A proteomics approach
Jacob Jaffe, Broad Institute, Cambridge, Massachusetts, USA
11:10 2.4 Analysis of the relationship between O-GlcNAc and polycomb-mediated transcriptional regulation in embryonic stem cell maintenance
Samuel Myers, University of California, San Francisco, California, USA
11:50 2.5 Large scale analysis of synaptic phosphorylation and O-GlcNAcylation reveals complex interplay between these post-translational modifications.
Jonathan Trinidad, University of California, San Francisco, California, USA
12:30pm Lunch

Chair: Lan Huang, University of California, Irvine, California, USA

2:00 2.6 Global kinetics analysis of the apoptotic caspases via targeted proteomics
Nicholas Agard, Codexis, Inc., Redwood City, California, USA
2:40 2.7 Defining the druggable cysteinome
Jack Taunton, University of California, San Francisco, California, USA
3:20 2.8 Modification site assignment scoring: Phosphorylation and beyond
Robert Chalkley, University of California, San Francisco, California, USA

Symposium Poster Session B
Monterey & Carmel Rooms

Co-Chairs: Katalin Medzihradszky and Victoria Pando, University of California, San Francisco, California, USA

4:00 Poster Session B

Wednesday, August 24

Symposium
Nikko Ballroom

Chair: Jonathan Trinidad, University of California, San Francisco, California, USA

8:30am 3.1 Receptor tyrosine kinases: Devolving signaling components with phosphoproteomics
Ralph A. Bradshaw, University of California, San Francisco, California, USA
9:10 3.2 Chemical genetic approach for kinase substrate identification reveals novel substrates of NDR1 and uncovers their role in controlling dendrite arborization and synapse maturation
Nicholas Hertz, University of California, San Francisco, California, USA
9:50 3.3 Phosphoproteomics reveals multiple Aurora substrates involved in chromatin dynamics
Boris Maček, Proteome Center Tuebingen, Tuebingen, Germany
10:30 Coffee break

Chair: A.L. Burlingame, University of California, San Francisco, California, USA

10:50 3.4 Plenary Lecture
Discovery and targeted proteomic approaches for the study of aging and age-related diseases
Bradford W. Gibson, Buck Institute for Research on Aging, Novato, California, USA
11:50 Lunch

Chair: Jeffrey Gorman, Queensland Institute of Medical Research, Herston, Australia

1:20pm 3.5 Defining protein interaction networks of protein complexes to understand their function and regulation
Lan Huang, University of California, Irvine, California, USA
2:00 3.6 Sampling the topography of protein complexes by chemical crosslinking in conjunction with high resolution ETD-MS/MS analysis
Michael Trnka, University of California, San Francisco, California, USA

Symposium Poster Session C
Monterey & Carmel Rooms

Co-Chairs: Robert Chalkley and Juan Oses, University of California, San Francisco, California, USA

2:40 Poster Session C

Conference Dinner
Julia Morgan Ballroom

6:00pm Conference Dinner Reception
Julia Morgan Ballroom
7:00 Conference Dinner
Julia Morgan Ballroom

Thursday, August 25

Symposium
Nikko Ballroom

Chair: Juan Oses, University of California, San Francisco, California, USA

8:30am 4.1 Development of a physicochemically diverse peptide library for multiplexed profiling of protease specificity
Giselle Knudsen, University of California, San Francisco, California, USA
9:10 4.2 Targeted identification of SUMOylation sites in human cells using affinity enrichment and paralog-specific reporter ions on a LTQ-Orbitrap Velos
Pierre Thibault, University of Montreal, Quebec, Canada
9:50 4.3 Mass spectrometry approaches for profiling ubiquitination
Donald S. Kirkpatrick, Genentech, Inc., S. San Francisco, California, USA
10:30 Coffee break
11:00 4.4 Methods for characterizing protein ubiquitination in whole cell lysates
Namrata Udeshi, Broad Institute, Cambridge, Massachusetts, USA
11:40 Lunch

Chair: Giselle Knudsen, University of California, San Francisco, California, USA

1:40pm 4.5 Interactions of paramyxoviruses with host cell proteins
Jeffrey Gorman, Queensland Institute of Medical Research, Herston, Australia
2:20 4.6 Discovery of antiviral roles of Mammalian Sirtuins: A systems biology view
Ileana Cristea, Princeton University, New Jersey, USA
3:00 4.7 Assessing the mechanism of action of tyrosine kinase inhibitors using quantitative phosphoproteomic mass spectrometry
Jennifer Gajan, University of California, San Francisco, California, USA

Chair: John Stults, Genentech, Inc., South San Francisco, California, USA

3:40 4.8 Plenary Lecture
Novel predictors of cardiometabolic diseases
Robert E. Gerszten, Massachusetts General Hospital, Boston, Massachusetts, USA

 

4:40 Closing remarks
5:00pm Adjourn

 


last modified Wed Aug 17 17:47:50 2011 PDT